Any time that an IMOT model was studied, in comparison to a control group utilizing traditional therapy, the IMOT participants saw better results than their controlled peers. This Journal of Child Neurology 2014 article summarizes 19 such studies
, all of which showed strong evidence for intensive therapy improving function and plasticity. The therapy dose in the studies varied from 40 to 120 hours and was augmented by a home program.
Example of such studies are a 2007 Emory University School of Medicine study
focused on children with hemiplegic CP, where those taking part in a 2-week intensive, accompanied by a month-long 1-2 hr/day daily home program, were compared to a control group. The treated children all saw improvements in 11 out of the 12 functions being tested, whereas the control group remained unchanged. Another example is a 2017 Bond University study
that assessed children with varying neurological conditions over the span of a 3-week intensive (2-6 hrs/day). The results showed a GAS (Goal Attainment Scale) 176% increase in physical function relating to mobility goals.